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ProtiPrep Pop2 Spin Column - 24 Pack

- Description
ProtiPrep Pop2 is a ready-to-use microspin column that depletes the five most abundant plasma proteins in just 5 minutes. Designed for modern proteomics workflows, it simplifies your sample prep with unmatched speed, reliability, and ease of use. Ideal for mass spectrometry and biomarker discovery.
Product Specifications
Parameter | Detail |
Sample Volume | 10 µL plasma |
Output Volume | ~150 µL depleted plasma |
Purification Target | Human serum albumin (HSA), Immunoglobulin G (IgG) |
Format | Preloaded microspin column with resin and PBS buffer (pH 7.4, 0.02% NaN₃) |
Quantity | 24 columns per pack (12-pack also available) |
Centrifuge | Compatible with standard benchtop units ≥10,000 x g |
Shelf Life | 6 months at 4–8 °C |
Storage | Store refrigerated at 4–8 °C. Do not freeze. |
Shipping Conditions | Shipped refrigerated |
Key features:
- High-efficiency depletion: Removes >98% of Albumin, IgG
- Fast workflow: Load – mix – spin. Done in 5 minutes.
- Low sample input: Works with 10 µL of plasma
- Max recovery: Up to 150 µL clean flow-through for downstream use
- Ready-to-use: No setup, buffers, or regeneration needed
- MS-compatible: No interfering substances
Preloaded spin columns with buffer-flush activation for 5-minute depletion of HSA and IgG from plasma
ProtiPrep Pop2 is a fully integrated, ready-to-use microspin column for the rapid depletion of human serum albumin (HSA) and immunoglobulin G (IgG): the two most abundant proteins in plasma. Designed with a unique built-in buffer compartment, Pop2 activates upon use by flushing phosphate-buffered saline (PBS) across the resin bed, priming it for immediate sample loading.
To use Pop2, simply invert to release the buffer, then add 10 μL of plasma, shake gently, and incubate for 5 minutes. A quick spin separates the depleted sample into the collection tube: no equilibration, washing, or buffer preparation required.

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ProtiPrep Pop2 Spin Column - 12 Pack
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